to spurn: to reject a person or thing with open contempt, treating as worthless what deserves honor
This is a strong verb of contempt. It does not describe a passing dislike but a deliberate act of treating something honorable as if it were beneath notice, throwing it away with scorn. Its usual target is God: his own person, his worship, his word, or his name. When the Bible says a people spurned the LORD, it means they looked at the one they owed everything to and treated him as nothing.
Because the offense is aimed upward, at God, the word carries a note of provocation. To spurn God is not only an insult; it stirs his anger and invites judgment. That is why older translations often render it "provoke." The provoking, though, is done by contempt, not by mere nuisance.
The same contempt can be turned in other directions. It is used for spurning correction and instruction, the wisdom teacher's warning that a fool throws away the very reproof that would save him. It is used for dragging God's name into disrepute, so that outsiders sneer at it. And a few times God himself is the one who spurns, casting off in anger the people who first cast off him.
Across all of these the core holds steady: to treat with contempt what ought to be honored.